Pipeline

Pipeline

Akcea is advancing a mature pipeline to address the unmet needs and complex medical challenges of patients with serious and rare diseases using antisense technology.

Transthyretin amyloidosis (ATTR)

Pre-clinical
Phase 1
Phase 2
Phase 3
Registration
AKCEA-TTR-LRx
ATTR Amyloidosis (ATTR)
Pre-clinical

Cardiometabolic lipid disorders

Pre-clinical
Phase 1
Phase 2
Phase 3
Registration
Volanesorsen
Familial Chylomicronemia Syndrome (FCS)
Registration
Familial Partial Lipodystrophy (FPL)
Phase 3
AKCEA-APO(a)-LRx
Hyperlipoproteinemia(a) with CV Risk
Phase 2
AKCEA-ANGPTL3-LRx
Rare hyperlipidemias
Phase 2
NAFLD with Metabolic Complications
Phase 1
AKCEA-APOCIII-LRx
Hypertriglyceridemia with CV risk
Phase 2